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Article

Direct targets of Klf5 transcription factor contribute to the maintenance of mouse embryonic stem cell undifferentiated state.

BMC biology - 27 Sept 2010

Parisi Silvia, Cozzuto Luca, Tarantino Carolina, Passaro Fabiana, Ciriello Simona, Aloia Luigi, Antonini Dario, De Simone Vincenzo, Pastore Lucio, Russo Tommaso

Abstract excerpt

BACKGROUND: A growing body of evidence has shown that Krüppel-like transcription factors play a crucial role in maintaining embryonic stem cell (ESC) pluripotency and in governing ESC fate decisions. Krüppel-like factor 5 (Klf5) appears to play a critical role in these processes, but detailed knowledge of the molecular mechanisms of this function is still not completely addressed. RESULTS: By combining...

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Identifiers

PMID: 20875108
DOI: 10.1186/1741-7007-8-128
PMCID: PMC2955566

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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