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Article

Frequency of single nucleotide polymorphisms of CYP2D6 in the Czech population.

Cell biochemistry and function - 1 Jan 2000

Buzková Helena, Pechandová Kristina, Slanar Ondrej, Perlík Frantisek

Abstract excerpt

CYP2D6 is a member of cytochrome P450 enzymes that metabolise over 25% of commonly used drugs. Genetic polymorphisms can cause insufficient drug efficacy at usually administered doses or can be the cause of adverse drug reaction. CYP2D6 genotyping can be used to predict CYP2D6 phenotype and thereby explain some abnormalities in drug response and thus optimize pharmacotherapy. The aim of this study was to...

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Identifiers

PMID: 17311358
DOI: 10.1002/cbf.1402

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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