Article
CYP2D6 extensive, intermediate, and poor phenotypes and genotypes in a Polish population.
European journal of clinical pharmacology - 1 Nov 2002
Niewinski P, Orzechowska-Juzwenko K, Hurkacz M, Rzemislawska Z, Jaźwinska-Tarnawska E, Milejski P, Forkasiewicz Z
Abstract excerpt
OBJECTIVE: This study investigated the distribution of the CYP2D6 genotypes and phenotypes in a Polish population and compared the concordance of the two methods. METHODS: Six hundred unrelated healthy individuals from southwestern Poland were studied. The CYP2D6 phenotype was analyzed in 300 individuals using sparteine as a model drug. The CYP2D6 genotype was analyzed in 300 individuals by polymerase chain...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
