Article
EirA Is a Novel Protein Essential for Intracellular Replication of Coxiella burnetii.
Infection and immunity - 20 May 2020
Kuba Miku, Neha Nitika, Newton Patrice, Lee Yi Wei, Bennett-Wood Vicki, Hachani Abderrahman, De Souza David P, Nijagal Brunda, Dayalan Saravanan, Tull Dedreia, McConville Malcolm J, Sansom Fiona M, Newton Hayley J
Abstract excerpt
The zoonotic bacterial pathogen Coxiella burnetii is the causative agent of Q fever, a febrile illness which can cause a serious chronic infection. C. burnetii is a unique intracellular bacterium which replicates within host lysosome-derived vacuoles. The ability of C. burnetii to replicate within this normally hostile compartment is dependent on the activity of the Dot/Icm type 4B secretion system. In a previous...
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