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Article

Intra-erythrocyte cation concentrations in relation to the C1797T beta-adducin polymorphism in a general population.

Journal of human hypertension - 1 May 2007

Richart T, Thijs L, Kuznetsova T, Tikhonoff V, Zagato L, Lijnen P, Fagard R, Wang J, Bianchi G, Staessen J A

Abstract excerpt

Genetic variability in the ADD1 (Gly460Trp) and ADD2 (C1797T) subunits of the cytoskeleton protein adducin plays a role in the pathogenesis of hypertension, possibly via changes in intracellular cation concentrations. ADD2 1797CC homozygous men have decreased erythrocyte count and hematocrit. We investigated possible association between intra-erythrocyte cations and the adducin polymorphisms. In 259 subjects...

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Source

Identifiers

PMID: 17301826
DOI: 10.1038/sj.jhh.1002154

Genes

ADD2
ADD1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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