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Article

Role of the adducin family genes in human essential hypertension.

Journal of hypertension - 1 Mar 2005

Lanzani Chiara, Citterio Lorena, Jankaricova Maria, Sciarrone M Teresa, Barlassina Cristina, Fattori Stefania, Messaggio Elisabetta, Serio Clelia Di, Zagato Laura, Cusi Daniele, Hamlyn John M, Stella Alessandra, Bianchi Giuseppe, Manunta Paolo

Abstract excerpt

OBJECTIVE: In both humans and rats, polymorphisms of the alpha adducin (ADD1) gene are involved in renal sodium handling, essential hypertension and some of its organ complications. Adducin functions within cells as a heterodimer composed of various combinations of three subunits that are coded by three genes (ADD1, 2, 3) each located on a different chromosome. DESIGN: These characteristics provide the...

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Source

Identifiers

PMID: 15716695
DOI: 10.1097/01.hjh.0000160210.48479.78

Genes

ADD1
ADD3
DBP
ADD2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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