Article
Shugoshin 2 regulates localization of the chromosomal passenger proteins in fission yeast mitosis.
Molecular biology of the cell - 1 May 2007
Vanoosthuyse Vincent, Prykhozhij Sergey, Hardwick Kevin G
Abstract excerpt
Fission yeast has two members of the Shugoshin family, Sgo1 and Sgo2. Although Sgo1 has clearly been established as a protector of centromere cohesion in meiosis I, the roles of Sgo2 remain elusive. Here we show that Sgo2 is required to ensure proper chromosome biorientation upon recovery from a prolonged spindle checkpoint arrest. Consistent with this, Sgo2 is essential for maintaining the Passenger proteins on...
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