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Article

Experimental confirmation of a key role for non-optimal codons in protein export.

Biochemical and biophysical research communications - 30 Mar 2007

Zalucki Yaramah M, Jennings Michael P

Abstract excerpt

Non-optimal codons are defined by low usage and low abundance of corresponding tRNA, and have an established role in translational pausing to allow the correct folding of proteins. Our previous work reported a striking abundance of non-optimal codons in the signal sequences of secretory proteins exported via the sec-dependent pathway in Escherichia coli. In the current study the signal sequence of maltose-binding...

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Identifiers

PMID: 17291454
DOI: 10.1016/j.bbrc.2007.01.126

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MBP

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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