Article
Signal peptides: exquisitely designed transport promoters.
Molecular microbiology - 1 Sept 1994
Izard J W, Kendall D A
Abstract excerpt
Prokaryotic proteins destined for transport out of the cytoplasm typically contain an N-terminal extension sequence, called the signal peptide, which is required for export. It is evident that many secretory proteins utilize a common export system, yet the signal sequences themselves display very little primary sequence homology. In attempting to understand how different signal peptides are able to promote...
Topics
- Amino Acids
- Bacteria
- Bacterial Physiological Phenomena
- Bacterial Proteins
- Biological Transport
- Cell Membrane
- Escherichia coli
- Membrane Lipids
- Mutagenesis, Site-Directed
- Mutation
- Protein Conformation