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Article

Metabotropic glutamate receptor subtype-1 is essential for motor coordination in the adult cerebellum.

Neuroscience research - 1 Apr 2007

Nakao Harumi, Nakao Kazuki, Kano Masanobu, Aiba Atsu

Abstract excerpt

We previously demonstrated that metabotropic glutamate receptor-subtype 1 knockout [mGluR1 (-/-)] mice showed ataxic gait, deficient long-term depression and impaired synapse elimination and these phenotypes were rescued by introduction of an mGluR1 transgene with Purkinje cell-specific promoter (mGluR1-rescue mice). However, roles of mGluR1 in the adult brain remain elusive, mainly due to lack of conventional...

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Identifiers

PMID: 17270300
DOI: 10.1016/j.neures.2006.12.014

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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