Type 1 inositol 1,4,5-trisphosphate receptor knock-out mice: their phenotypes and their meaning in neuroscience and clinical practice.

doi:10.1007/s001090050370

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Article

Type 1 inositol 1,4,5-trisphosphate receptor knock-out mice: their phenotypes and their meaning in neuroscience and clinical practice.

Journal of molecular medicine (Berlin, Germany) - 1 May 1999

Matsumoto M, Nagata E

Abstract excerpt

Cytoplasmic calcium, which acts as a second messenger, is derived not only from outside the cell but also from intracellular stores. A receptor for inositol 1,4,5-trisphosphate (IP3), an intracellular second messenger, is located on these internal calcium stores and functions as a calcium releasi...

Topics

Animals
Ataxia
Brain
Calcium
Calcium Channels
Electrophysiology
Epilepsy
Inositol 1,4,5-Trisphosphate
Inositol 1,4,5-Trisphosphate Receptors
Mice
Mice, Knockout
Phenotype
Receptors, Cytoplasmic and Nuclear

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