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Article

Functional role of the Werner syndrome RecQ helicase in human fibroblasts.

Aging cell - 1 Feb 2007

Dhillon Kiranjit K, Sidorova Julia, Saintigny Yannick, Poot Martin, Gollahon Katherine, Rabinovitch Peter S, Monnat Raymond J

Abstract excerpt

Werner syndrome is an autosomal recessive human genetic instability and cancer predisposition syndrome that also has features of premature aging. We focused on two questions related to Werner syndrome protein (WRN) function in human fibroblasts: Do WRN-deficient fibroblasts have a consistent cellular phenotype? What role does WRN play in the recovery from replication arrest? We identified consistent cell...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 17266675
DOI: 10.1111/j.1474-9726.2006.00260.x

Genes

WRN

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Functional role of the Werner syndrome RecQ helicase in human fibroblasts.PMID 17266675Read ↗

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