Article
Fibrinogen gene haplotypes in relation to risk of coronary events and coronary and extracoronary atherosclerosis: the Rotterdam Study.
Thrombosis and haemostasis - 1 Feb 2007
Kardys Isabella, Uitterlinden André G, Hofman Albert, Witteman Jacqueline C M, de Maat Moniek P M
Abstract excerpt
Fibrin network structure has been correlated with coronary disease. Fibrinogen gamma and alpha (FGG and FGA) gene haplotypes (chromosome 4q28) may be associated with fibrin network structure, and thereby with rigidity of the fibrin clot and sensitivity of the fibrin clot to the fibrinolytic system. Through these mechanisms they may influence risk of cardiovascular disease. We set out to investigate the relation...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
