Article
Fibrinogen genes and myocardial infarction: a haplotype analysis.
Arteriosclerosis, thrombosis, and vascular biology - 1 Apr 2008
Koch Werner, Hoppmann Petra, Biele Janita, Mueller Jakob C, Schömig Albert, Kastrati Adnan
Abstract excerpt
OBJECTIVE: Fibrinogen has a role in inflammatory processes and participates in atherosclerotic plaque formation. Despite intensive investigation, there is no clear evidence for a role of variations in the genes coding for the fibrinogen-alpha, fibrinogen-beta, and fibrinogen-gamma polypeptide chains in myocardial infarction. We examined the association of haplotypes in the 50-kb fibrinogen gene region with...
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