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Article

Associations between common fibrinogen gene polymorphisms and cardiovascular disease in older adults. The Cardiovascular Health Study.

Thrombosis and haemostasis - 1 Feb 2008

Carty Cara L, Cushman Mary, Jones Daniel, Lange Leslie A, Hindorff Lucia A, Rice Kenneth, Jenny Nancy S, Durda J Peter, Walston Jeremy, Carlson Christopher S, Nickerson Debbie, Tracy Russell P, Reiner Alex P

Abstract excerpt

Elevated plasma fibrinogen is a risk factor for cardiovascular disease (CVD), but associations between fibrinogen single nucleotide polymorphisms (SNPs) and disease risk are inconsistent. We investigated whether common (> or = 5% minor allele frequency) variation in the fibrinogen genes (FGA, FGB, FGG) is associated with fibrinogen concentration, carotid artery intima-medial thickness (IMT) and risk of incident...

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Identifiers

PMID: 18278190
DOI: 10.1160/TH07-08-0523

Genes

FGA
FGB
FGG

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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