Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Assessment of genetic determinants of the association of γ' fibrinogen in relation to cardiovascular disease.

Arteriosclerosis, thrombosis, and vascular biology - 1 Oct 2011

Lovely Rehana S, Yang Qiong, Massaro Joseph M, Wang Jing, D'Agostino Ralph B, O'Donnell Christopher J, Shannon Jackilen, Farrell David H

Abstract excerpt

OBJECTIVE: γ' fibrinogen is a newly emerging biomarker that is associated with cardiovascular disease (CVD). However, the genetic determinants of γ' fibrinogen levels are unknown. We therefore conducted a genome-wide association study on 3042 participants from the Framingham Heart Study Offspring Cohort. METHODS AND RESULTS: A genome-wide association study with 2.5 million single-nucleotide polymorphisms (SNPs)...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cardiovascular Diseases
Share to Cohort Studies

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Fibrinogens, Abnormal

Share to Logistic Models

Share to Massachusetts

Share to Odds Ratio

Share to Prevalence

Share to Risk Assessment

Source

Open in PubMed Open full text

Identifiers

PMID: 21757653
DOI: 10.1161/ATVBAHA.111.232710
PMCID: PMC3174319

Genes

FGB
FGG

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Assessment of genetic determinants of the association of γ' fibrinogen in relation to cardiovascular disease.PMID 21757653Read ↗

Multiethnic meta-analysis of genome-wide association studies in >100 000 subjects identifies 23 fibrinogen-associated Loci but no strong evidence of a causal association between circulating fibrinogen and cardiovascular disease.Semantic proximity Read ↗

Associations between common fibrinogen gene polymorphisms and cardiovascular disease in older adults. The Cardiovascular Health Study.Semantic proximity Read ↗

Association of novel genetic Loci with circulating fibrinogen levels: a genome-wide association study in 6 population-based cohorts.Semantic proximity Read ↗

Association of genomic loci from a cardiovascular gene SNP array with fibrinogen levels in European Americans and African-Americans from six cohort studies: the Candidate Gene Association Resource (CARe).Semantic proximity Read ↗

Identification of gene-gene and gene-environment interactions within the fibrinogen gene cluster for fibrinogen levels in three ethnically diverse populations.Semantic proximity Read ↗

Association between patterns of nucleotide variation across the three fibrinogen genes and plasma fibrinogen levels: the Coronary Artery Risk Development in Young Adults (CARDIA) study.Semantic proximity Read ↗

Whole genome analysis of plasma fibrinogen reveals population-differentiated genetic regulators with putative liver rolesSemantic proximity Read ↗

Fibrinogen as a Pleiotropic Protein Causing Human Diseases: The Mutational Burden of Aα, Bβ, and γ Chains.Semantic proximity Read ↗

Whole-genome analysis of plasma fibrinogen reveals population-differentiated genetic regulators with putative liver roles.Semantic proximity Read ↗

A genome-wide search for genes affecting circulating fibrinogen levels in the Framingham Heart Study.Semantic proximity Read ↗

Fibrinogen gene haplotypes in relation to risk of coronary events and coronary and extracoronary atherosclerosis: the Rotterdam Study.Semantic proximity Read ↗

The contribution of genetic and environmental factors to changes in total and γ' fibrinogen over 5 years.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.