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Article

A genome-wide search for genes affecting circulating fibrinogen levels in the Framingham Heart Study.

Thrombosis research - 15 Apr 2003

Yang Qiong, Tofler Geoffrey H, Cupples L Adrienne, Larson Martin G, Feng DaLi, Lindpaintner Klaus, Levy Daniel, D'Agostino Ralph B, O'Donnell Christopher J

Abstract excerpt

INTRODUCTION: Circulating levels of fibrinogen are associated with atherosclerosis and predict future coronary heart disease and stroke. Levels of fibrinogen are correlated among family members, suggesting a heritable component. Variants of the beta-fibrinogen gene subunit on 4q28 are associated with fibrinogen levels but explain only a small proportion of the total genetic variability. It remains unknown what...

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PMID: 12877910
DOI: 10.1016/s0049-3848(03)00288-3

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A genome-wide search for genes affecting circulating fibrinogen levels in the Framingham Heart Study.PMID 12877910Read ↗

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