Article
An investigation of polymorphisms in the 4q1 3.3-21.1 CXC chemokine gene cluster for association with multiple sclerosis in Australians.
Multiple sclerosis (Houndmills, Basingstoke, England) - 1 Dec 2006
Bugeja M J, Booth D R, Bennetts B H, Heard R N S, Stewart G J
Abstract excerpt
Susceptibility to multiple sclerosis (MS) is believed to result from the complex interaction of a number of genes, each with modest effect. Vital to the migration of cells to sites of inflammation, including the central nervous system, are chemokines, many of which are implicated in MS pathogenesis. Most of the CXC chemokine genes are encoded in a cluster on chromosome 4q13.3-21.1, which has been identified in...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.