Article
Lack of association between monocyte protein-1 (MCP-1) -2518 A>G chemoattractant and C-C chemokine receptor 2 (CCR2) Val64Ile polymorphisms and multiple sclerosis in a Tunisian population.
Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia - 1 Oct 2010
Messadi A, Fekih-Mrissa N, Kallel A, Bouguerra C, Sediri Y, Zaweli J, Laayouni S, Nciri B, Yedeas M, Mrissa R, Jemaa R, Kaabachi N, Gritli N
Abstract excerpt
Chemokines and their receptors are known to mediate inflammation and tissue damage in autoimmune disorders such as multiple sclerosis (MS). Multiple sclerosis is an inflammatory disease of the central nervous system, characterized by myelin damage and neurological complications. Monocyte chemoattractant protein-1 (MCP-1) interacts with the C-C chemokine receptor 2 (CCR2) and plays a role in the migration of...
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