Article
Follow-up examination of linkage and association to chromosome 1q43 in multiple sclerosis.
Genes and immunity - 1 Oct 2009
McCauley J L, Zuvich R L, Bradford Y, Kenealy S J, Schnetz-Boutaud N, Gregory S G, Hauser S L, Oksenberg J R, Mortlock D P, Pericak-Vance M A, Haines J L
Abstract excerpt
Multiple sclerosis (MS) is a debilitating neuroimmunological and neurodegenerative disease affecting >4,00,000 individuals in the United States. Population and family-based studies have suggested that there is a strong genetic component. Numerous genomic linkage screens have identified regions of interest for MS loci. Our own second-generation genome-wide linkage study identified a handful of non-major...
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