Article

An investigation of genetic polymorphisms in Heparan Sulfate Proteoglycan core proteins and key modification enzymes in an Australian Caucasian multiple sclerosis population

2020-04-08

Abstract excerpt

<title>Abstract</title> <p>Multiple Sclerosis (MS) is a chronic inflammatory demyelinating disease affecting the central nervous system in young adults. Heparan sulfate proteoglycans (HSPGs) are ubiquitous to the cell surface and the extracellular matrix. HSPG biosynthesis is a complex process involving enzymatic attachment of heparan sulfate (HS) chains to a core protein. HS side chains mediate specific ligand a...

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Literature Corpus work: be6a7fc7-a74a-515d-92f2-24204488b197
DOI: 10.21203/rs.2.23090/v2

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