Article
Genetic variation at the chromosome 16 chemokine gene cluster: development of a strategy for association studies in complex disease.
Annals of human genetics - 1 Sept 2003
Fisher S A, Moody A, Mirza M M, Cuthbert A P, Hampe J, Macpherson A, Sanderson J, Forbes A, Mansfield J, Schreiber S, Lewis C M, Mathew C G
Abstract excerpt
The chemokine gene cluster [CCL22, CX3CL1, CCL17] (previously known as [SCYA22, SCYD1, SCYA17]) is a candidate locus for one of the susceptibility genes for inflammatory bowel disease that are located in the peri-centromeric region of chromosome 16. Screening for sequence variation at this locus led to the detection of 14 single nucleotide polymorphisms (SNPs). An efficient experimental and computational approach...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
