Article
An investigation of polymorphisms in the 17q11.2-12 CC chemokine gene cluster for association with multiple sclerosis in Australians.
BMC medical genetics - 26 Jul 2006
Bugeja Matthew J, Booth David, Bennetts Bruce, Heard Robert, Rubio Justin, Stewart Graeme
Abstract excerpt
BACKGROUND: Multiple sclerosis (MS) is a disorder of the central nervous system (CNS) characterised by inflammation and neuronal degeneration. It is believed to result from the complex interaction of a number of genes, each with modest effect. Chemokines are vital to the migration of cells to sites of inflammation, including the CNS, and many are implicated in MS pathogenesis. Most of the CC chemokine genes are...
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