Article
A common genetic variant rs2821557 in KCNA3 is linked to the severity of multiple sclerosis.
Journal of neuroscience research - 1 Jan 2021
Lioudyno Victoria, Abdurasulova Irina, Negoreeva Irina, Stoliarov Igor, Kudriavtsev Igor, Serebryakova Maria, Klimenko Victor, Lioudyno Maria
Abstract excerpt
The rate of symptom accumulation distinguishes between slowly and rapidly progressing forms of multiple sclerosis (MS). Given that a patient's genetics can affect the rate of disease progression, identification of genetic variants associated with rapid disease progression should provide valuable information for timely prognosis and development of optimal treatment plans. We hypothesized that the polymorphism...
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