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Article

MDR1 polymorphisms and response to azathioprine therapy in patients with Crohn's disease.

Inflammatory bowel diseases - 1 May 2007

Mendoza Juan L, Urcelay Elena, Lana Raquel, Martín M Carmen, López Natalia, Guijarro Luis G, Mayol Julio A, Taxonera Carlos, de la Concha Emilio G, Peña Amado S, Díaz-Rubio Manuel

Abstract excerpt

BACKGROUND: To investigate the contribution of multidrug resistance 1 (MDR1) gene pharmacogenetics (G2677T/A and C3435T) to the efficacy of azathioprine in inducing remission in patients with Crohn's disease (CD). METHODS: A cohort of 327 unrelated Spanish patients with CD recruited from a single center was studied. All patients were rigorously followed up for at least 2 years (mean time, 11.5 years). A...

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Identifiers

PMID: 17262810
DOI: 10.1002/ibd.20044

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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