Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The frequency of C3435T MDR1 gene polymorphism in Iranian patients with ulcerative colitis.

International journal of colorectal disease - 1 Sept 2007

Farnood Alma, Naderi Nosratollah, Moghaddam Seyed Javad Mirhasani, Noorinayer Babak, Firouzi Farzad, Aghazadeh Rahim, daryani Nasser Ebrahimi, Zali Mohammad Reza

Abstract excerpt

BACKGROUND AND AIMS: The MDR1 (multidrug resistance) gene, located on chromosome 7, is in one of the inflammatory bowel disease susceptibility loci. It produces P-glycoprotein, a transmembrane efflux pump, transferring drugs and toxins from intracellular to extracellular domains. In the human gastrointestinal (GI) tract, P-glycoprotein is found in high concentrations on the epithelial cells of the colon and small...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to ATP Binding Cassette Transporter, Subfamily B, Member 1
Share to Case-Control Studies

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Chromosomes, Human, Pair 7

Share to Colitis, Ulcerative

Share to Gene Frequency

Share to Genes, MDR

Share to Polymorphism, Genetic

Source

Identifiers

PMID: 17242936
DOI: 10.1007/s00384-007-0270-6

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The frequency of C3435T MDR1 gene polymorphism in Iranian patients with ulcerative colitis.PMID 17242936Read ↗

Effect of the C3435T polymorphism of the multidrug resistance 1 gene on the severity of inflammatory bowel disease in Iranian Azeri Turks.Semantic proximity Read ↗

MDR1 C3435T polymorphism and inflammatory bowel disease risk: a meta-analysis.Semantic proximity Read ↗

[Is C3435T polymorphism of MDR1 related to inflammatory bowel disease or colorectal cancer in Korean?].Semantic proximity Read ↗

Association between the C3435T MDR1 gene polymorphism and susceptibility for ulcerative colitis.Semantic proximity Read ↗

MDR1 polymorphisms are associated with inflammatory bowel disease in a cohort of Croatian IBD patients.Semantic proximity Read ↗

C3435T Polymorphism of the ABCB1/MDR1 gene encoding P-glycoprotein in patients with inflammatory bowel disease in a Polish populationSemantic proximity Read ↗

C3435T Polymorphism of the ABCB1 Gene in Polish Patients with Inflammatory Bowel Disease: A Case-Control and Meta-Analysis Study.Semantic proximity Read ↗

Association of the colorectal cancer and MDR1 gene polymorphism in an Iranian population.Semantic proximity Read ↗

MDR1 gene: susceptibility in Spanish Crohn's disease and ulcerative colitis patients.Semantic proximity Read ↗

Multidrug resistance 1 gene in inflammatory bowel disease: a meta-analysis.Semantic proximity Read ↗

Association between MDR1 C3435T polymorphism and colorectal cancer risk: A meta-analysis.Semantic proximity Read ↗

Effects of polymorphism in G2677T/A triallelic region of MDR1 gene in Turkish patients with inflammatory bowel disease.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.