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Article

Liver X receptors regulate dendritic cell phenotype and function through blocked induction of the actin-bundling protein fascin.

Blood - 15 May 2007

Geyeregger René, Zeyda Maximilian, Bauer Wolfgang, Kriehuber Ernst, Säemann Marcus D, Zlabinger Gerhard J, Maurer Dieter, Stulnig Thomas M

Abstract excerpt

Liver X receptors (LXRs) are nuclear receptors regulating lipid and cholesterol metabolism. Recent data revealed a cross talk between LXR and Toll-like receptor signaling in macrophages, indicating a role in immunity. Here, we show that LXRalpha is expressed in human myeloid dendritic cells (DCs) and induced during differentiation of monocyte-derived DCs, whereas LXRbeta is expressed constitutively at a very low...

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Identifiers

PMID: 17255360
DOI: 10.1182/blood-2006-08-043422

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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