Article
Research resource: transcriptome profiling of genes regulated by RXR and its permissive and nonpermissive partners in differentiating monocyte-derived dendritic cells.
Molecular endocrinology (Baltimore, Md.) - 1 Nov 2010
Széles Lajos, Póliska Szilárd, Nagy Gergely, Szatmari Istvan, Szanto Attila, Pap Attila, Lindstedt Malin, Santegoets Saskia J A M, Rühl Ralph, Dezsö Balázs, Nagy László
Abstract excerpt
Retinoid X receptors (RXRs) are heterodimerization partners for many nuclear receptors and also act as homodimers. Heterodimers formed by RXR and a nonpermissive partner, e.g. retinoic acid receptor (RAR) and vitamin D receptor (VDR), can be activated only by the agonist of the partner receptor. In contrast, heterodimers that contain permissive partners, e.g. liver X receptor (LXR) and peroxisome...
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