Article
Rank ligand stimulation induces a partial but functional maturation of human monocyte-derived dendritic cells.
European cytokine network - 1 Jun 2008
Schiano de Colella Jean-Marc, Barbarat Bernadette, Sweet Ray, Gastaut Jean-Albert, Olive Daniel, Costello Regis T
Abstract excerpt
Mature dendritic cells (DC) are efficient, antigen-presenting cells required for the stimulation of naive T lymphocytes. Many members of the tumour necrosis factor (TNF) receptor family are involved in DC maturation, such as Fas, CD40, OX40L, LIGHT (homologous to lymphotoxins, exhibits inducible expression, and competes with HSV glycoprotein D for herpes virus entry mediator (HVEM), a receptor expressed by T...
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