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Article

Frequency-dependent contractile strength in mice over- and underexpressing the sarco(endo)plasmic reticulum calcium-ATPase.

American journal of physiology. Regulatory, integrative and comparative physiology - 1 Jul 2007

Hiranandani Nitisha, Raman Sripriya, Kalyanasundaram Anuradha, Periasamy Muthu, Janssen Paul M L

Abstract excerpt

One of the prominent markers of end-stage heart failure at the molecular level is a decrease in function and/or expression of the sarcoplasmic reticulum ATPase protein [sarco(endo)plasmic reticulum calcium-ATPase, SERCA]. It has been often postulated that a decrease in SERCA pump activity can contribute in a major way to decreased cardiac function. To establish a functional relationship, we assessed how...

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PMID: 17255213
DOI: 10.1152/ajpregu.00508.2006

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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