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Article

T cell receptor binding transition states and recognition of peptide/MHC.

Biochemistry - 20 Feb 2007

Davis-Harrison Rebecca L, Insaidoo Francis K, Baker Brian M

Abstract excerpt

T cell receptor recognition of peptide/MHC has been described as proceeding through a "two-step" process in which the TCR first contacts the MHC molecule prior to formation of the binding transition state using the germline-encoded CDR1 and CDR2 loops. The receptor then contacts the peptide using...

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Source

Identifiers

PMID: 17249694
DOI: 10.1021/bi061702p

Genes

CDR2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-17249694-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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