Article
[Resistance-conferring mutations of Mycobacterium tuberculosis strains with low level resistance to isoniazid].
Kekkaku : [Tuberculosis] - 1 Dec 2006
Ano Hiromi, Matsumoto Tomoshige, Nagai Takayuki, Tamura Yoshitaka, Yoshida Hiroko, Kawahara Kunimitsu, Takamatsu Isamu, Tsuyuguchi Izuo, Takashima Tetsuya
Abstract excerpt
OBJECTIVE: We investigated the prevalence of isoniazid (INH) resistance-conferring mutations in the INH-indeterminate Mycobacterium tuberculosis (MTB) strains. MATERIALS AND METHODS: We initially selected a sample of 47 clinical isolates of MTB from patients, who visited the Osaka Prefectural Medical Center for Respiratory and Allergic Diseases from 2000 to 2005. Strains resistant to the concentration of 1 - 2...
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