Article
miles-apart-Mediated regulation of cell-fibronectin interaction and myocardial migration in zebrafish.
Nature clinical practice. Cardiovascular medicine - 1 Feb 2007
Matsui Takaaki, Raya Angel, Callol-Massot Carles, Kawakami Yasuhiko, Oishi Isao, Rodriguez-Esteban Concepcion, Izpisúa Belmonte Juan Carlos
Abstract excerpt
The migration of myocardial precursor cells towards the embryonic midline underlies the formation of the heart tube and is a key process of heart organogenesis. The zebrafish mutation miles-apart (mil), which affects the gene encoding a sphingosine-1-phosphate receptor, is characterized by defective migration of myocardial precursor cells and results in the formation of two laterally positioned hearts, a...
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