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Article

Endoderm convergence controls subduction of the myocardial precursors during heart-tube formation

1 Sept 2015

Abstract excerpt

Coordination between the endoderm and adjacent cardiac mesoderm is crucial for heart development. We previously showed that myocardial migration is promoted by convergent movement of the endoderm, which itself is controlled by the S1pr2/Gα13 signaling pathway, but it remains unclear how the movements of the two tissues is coordinated. Here, we image live and fixed embryos to follow these movements, revealing...

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PMID: 26329600
DOI: 10.1242/dev.113944

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