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Article

The yolk syncytial layer regulates myocardial migration by influencing extracellular matrix assembly in zebrafish

28 Sept 2006

Abstract excerpt

The roles of extra-embryonic tissues in early vertebrate body patterning have been extensively studied, yet we know little about their function during later developmental events. Here, we analyze the function of the zebrafish extra-embryonic yolk syncytial layer (YSL) specific transcription factor, Mtx1, and find that it plays an essential role in myocardial migration. Downregulating the function of Mtx1 in the...

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PMID: 17008449
DOI: 10.1242/dev.02581

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