Article
A sphingosine-1-phosphate receptor regulates cell migration during vertebrate heart development.
Nature - 13 Jul 2000
Kupperman E, An S, Osborne N, Waldron S, Stainier D Y
Abstract excerpt
Coordinated cell migration is essential in many fundamental biological processes including embryonic development, organogenesis, wound healing and the immune response. During organogenesis, groups of cells are directed to specific locations within the embryo. Here we show that the zebrafish miles apart (mil) mutation specifically affects the migration of the heart precursors to the midline. We found that mutant...
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