Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Stem cells transform into a cardiac phenotype with remodeling of the nuclear transport machinery.

Nature clinical practice. Cardiovascular medicine - 1 Feb 2007

Perez-Terzic Carmen, Faustino Randolph S, Boorsma Brian J, Arrell D Kent, Niederländer Nicolas J, Behfar Atta, Terzic Andre

Abstract excerpt

Nuclear transport of transcription factors is a critical step in stem cell commitment to a tissue-specific lineage. While it is recognized that nuclear pores are gatekeepers of nucleocytoplasmic exchange, it is unknown how the nuclear transport machinery becomes competent to support genetic reprogramming and cell differentiation. Here, we report the dynamics of nuclear transport factor expression and nuclear pore...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Active Transport, Cell Nucleus
Share to Cell Differentiation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cells, Cultured

Share to Embryonic Stem Cells

Share to Myocytes, Cardiac

Share to Nuclear Pore

Share to Phenotype

Source

Identifiers

PMID: 17230218
DOI: 10.1038/ncpcardio0763

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Stem cells transform into a cardiac phenotype with remodeling of the nuclear transport machinery.PMID 17230218Read ↗

Intercellular Transfer of PTBP1 Drives Human Neural Stem Cell FateSemantic proximity Read ↗

Interactome of a cardiopoietic precursor.Semantic proximity Read ↗

Deciphering the Epigenetic Code of Cardiac Myocyte TranscriptionSemantic proximity Read ↗

Spatial proteomic mapping of human nuclear bodies reveals new functional insights into RNA regulationSemantic proximity Read ↗

Putting things in place for fertilization: discovering roles for importin proteins in cell fate and spermatogenesisSemantic proximity Read ↗

In vivo proximity proteomics uncovers palmdelphin (PALMD) as a Z-line-associated mitigator of isoproterenol-induced cardiac injurySemantic proximity Read ↗

Analysis of the initiation of nuclear pore assembly by ectopically targeting nucleoporins to chromatin.Semantic proximity Read ↗

Blending and separating dynamics of RNA-binding proteins develop architectural splicing networks spreading throughout the nucleus.Semantic proximity Read ↗

Nuclear pore complex composition: a new regulator of tissue-specific and developmental functions.Semantic proximity Read ↗

Directed inhibition of nuclear import in cellular hypertrophy.Semantic proximity Read ↗

Architectural control of mesenchymal stem cell phenotype through nuclear actin.Semantic proximity Read ↗

The role of nuclear pores in gene regulation, development and diseaseSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.