Nuclear pore complex composition: a new regulator of tissue-specific and developmental functions.

doi:10.1038/nrm3461

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Article

Nuclear pore complex composition: a new regulator of tissue-specific and developmental functions.

Nature reviews. Molecular cell biology - 1 Nov 2012

Raices Marcela, D'Angelo Maximiliano A

Abstract excerpt

Nuclear pore complexes (NPCs) are multiprotein aqueous channels that penetrate the nuclear envelope connecting the nucleus and the cytoplasm. NPCs consist of multiple copies of roughly 30 different proteins known as nucleoporins (NUPs). Due to their essential role in controlling nucleocytoplasmic transport, NPCs have traditionally been considered as structures of ubiquitous composition. The overall structure of...

Topics

Active Transport, Cell Nucleus
Animals
Cell Nucleus
Cytoplasm
Drosophila melanogaster
Genetic Variation
Humans
Nuclear Envelope
Nuclear Pore
Nuclear Pore Complex Proteins

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Open in PubMed

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PMID: 23090414
DOI: 10.1038/nrm3461

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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