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Spatial proteomic mapping of human nuclear bodies reveals new functional insights into RNA regulation

2024-07-03

Abstract excerpt

Nuclear bodies are diverse membraneless suborganelles with emerging links to development and disease. Explaining their structure, function, regulation, and implications in human health will require understanding their protein composition; however, isolating nuclear bodies for proteomic analysis remains challenging. We present the first comprehensive proximity proteomics-based map of nuclear bodies, featuring 140 b...

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Identifiers and source

Literature Corpus work
5f563712-306e-530b-b1a6-569a072f7ddd
DOI
10.1101/2024.07.03.601239
Open publication

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Spatial proteomic mapping of human nuclear bodies reveals new functional insights into RNA regulationDOI 10.1101/2024.07.03.601239
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