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Article

Analysis of the initiation of nuclear pore assembly by ectopically targeting nucleoporins to chromatin.

Nucleus (Austin, Tex.) - 1 Jan 2015

Schwartz Michal, Travesa Anna, Martell Steven W, Forbes Douglass J

Abstract excerpt

Nuclear pore complexes (NPCs) form the gateway to the nucleus, mediating virtually all nucleocytoplasmic trafficking. Assembly of a nuclear pore complex requires the organization of many soluble sub-complexes into a final massive structure embedded in the nuclear envelope. By use of a LacI/LacO reporter system, we were able to assess nucleoporin (Nup) interactions, show that they occur with a high level of...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 25602437
DOI: 10.1080/19491034.2015.1004260
PMCID: PMC4615246

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CFP

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