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Article

Putting things in place for fertilization: discovering roles for importin proteins in cell fate and spermatogenesis

1 Jan 2015

Abstract excerpt

Importin proteins were originally characterized for their central role in protein transport through the nuclear pores, the only intracellular entry to the nucleus. This vital function must be tightly regulated to control access by transcription factors and other nuclear proteins to genomic DNA, to achieve appropriate modulation of cellular behaviors affecting cell fate. Importin-mediated nucleocytoplasmic...

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PMID: 25994647
DOI: 10.4103/1008-682x.154310

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