Article
Directed inhibition of nuclear import in cellular hypertrophy.
The Journal of biological chemistry - 8 Jun 2001
Perez-Terzic C, Gacy A M, Bortolon R, Dzeja P P, Puceat M, Jaconi M, Prendergast F G, Terzic A
Abstract excerpt
Each nuclear pore is responsible for both nuclear import and export with a finite capacity for bidirectional transport across the nuclear envelope. It remains poorly understood how the nuclear transport pathway responds to increased demands for nucleocytoplasmic communication. A case in point is cellular hypertrophy in which increased amounts of genetic material need to be transported from the nucleus to the...
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