Article
BDNF tagging polymorphisms and haplotype analysis in sporadic Parkinson's disease in diverse ethnic groups.
Neuroscience letters - 19 Mar 2007
Xiromerisiou G, Hadjigeorgiou G M, Eerola J, Fernandez H H, Tsimourtou V, Mandel R, Hellström O, Gwinn-Hardy K, Okun M S, Tienari P J, Singleton A B
Abstract excerpt
Experimental and clinical data suggest that genetic variations in brain-derived neurotrophic factor (BDNF) gene may affect risk for Parkinson's disease (PD). We performed a case-control association analysis of BDNF in three independent Caucasian cohorts (Greek, North American, and Finnish) of PD using eight tagging SNPs and five constructed haplotypes. No statistically significant differences in genotype and...
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