Article
Serotonin and dopamine transporter genes do not influence depression in Parkinson's disease.
Movement disorders : official journal of the Movement Disorder Society - 15 Jan 2009
Dissanayaka Nadeeka N W, Silburn Peter A, O'Sullivan John D, Mellick George D
Abstract excerpt
Altered levels of the neurotransmitters dopamine and serotonin are observed in both Parkinson's disease (PD) and depression. Therefore, the neurotransmitter transporter genes, SLC6A3 (dopamine) and SLC6A4 (serotonin) are candidates for depression in PD. We genotyped 24 tagging SNPs together with VNTRs and the SLC6A4 LPR polymorphism in 190 PD patients categorised according to lifetime history of depression....
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
