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Article

Genetic analysis of BDNF and TrkB gene polymorphisms in Alzheimer's disease.

Journal of neurology - 1 Apr 2005

Vepsäläinen Saila, Castren Eero, Helisalmi Seppo, Iivonen Susan, Mannermaa Arto, Lehtovirta Maarit, Hänninen Tuomo, Soininen Hilkka, Hiltunen Mikko

Abstract excerpt

According to previous biochemical and genetic findings, brain-derived neurotrophic factor (BDNF), via activation of its tyrosine kinase receptor B (TrkB), is considered as a plausible candidate for contributing to Alzheimer's disease (AD). To examine the genetic association of BDNF and TrkB genes with AD, we genotyped multiple single nucleotide polymorphisms (SNPs) within these genes among 375 Finnish AD patients...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Share to Polymorphism, Genetic

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Source

Identifiers

PMID: 15726264
DOI: 10.1007/s00415-005-0667-5

Genes

BDNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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