Article
Genetic analysis of BDNF and TrkB gene polymorphisms in Alzheimer's disease.
Journal of neurology - 1 Apr 2005
Vepsäläinen Saila, Castren Eero, Helisalmi Seppo, Iivonen Susan, Mannermaa Arto, Lehtovirta Maarit, Hänninen Tuomo, Soininen Hilkka, Hiltunen Mikko
Abstract excerpt
According to previous biochemical and genetic findings, brain-derived neurotrophic factor (BDNF), via activation of its tyrosine kinase receptor B (TrkB), is considered as a plausible candidate for contributing to Alzheimer's disease (AD). To examine the genetic association of BDNF and TrkB genes...
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