Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Population genetic study of the brain-derived neurotrophic factor (BDNF) gene.

Molecular psychiatry - 1 Aug 2010

Petryshen T L, Sabeti P C, Aldinger K A, Fry B, Fan J B, Schaffner S F, Waggoner S G, Tahl A R, Sklar P

Abstract excerpt

Genetic variants in the brain-derived neurotrophic factor (BDNF) gene, predominantly the functional Val66Met polymorphism, have been associated with risk of bipolar disorder and other psychiatric disorders. However, not all studies support these findings, and overall the evidence for the association of BDNF with disease risk is weak. As differences in population genetic structure between patient samples could...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Brain-Derived Neurotrophic Factor
Share to Gene Frequency

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Genetics, Population

Share to Genotype

Share to Linkage Disequilibrium

Share to Methionine

Share to Polymorphism, Single Nucleotide

Share to Valine

Source

Open in PubMed Open full text

Identifiers

PMID: 19255578
DOI: 10.1038/mp.2009.24
PMCID: PMC2888876

Genes

BDNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Population genetic study of the brain-derived neurotrophic factor (BDNF) gene.PMID 19255578Read ↗

Associations of BDNF/BDNF-AS SNPs with Depression, Schizophrenia, and Bipolar DisorderSemantic proximity Read ↗

Genetic variation of brain-derived neurotrophic factor (BDNF) in bipolar disorder: case-control study of over 3000 individuals from the UK.Semantic proximity Read ↗

Family-based association study of 76 candidate genes in bipolar disorder: BDNF is a potential risk locus. Brain-derived neutrophic factor.Semantic proximity Read ↗

The BDNF Val66Met polymorphism and plasma brain-derived neurotrophic factor levels in Han Chinese patients with bipolar disorder and schizophrenia.Semantic proximity Read ↗

Effects of BDNF polymorphisms on brain function and behavior in health and disease.Semantic proximity Read ↗

Transmission distortion of BDNF variants to bipolar disorder type I patients from a South American population isolate.Semantic proximity Read ↗

Genetics of bipolar disorder: focus on BDNF Val66Met polymorphism.Semantic proximity Read ↗

BDNF Val66Met polymorphism and bipolar disorder in European populations: A risk association in case-control, family-based and GWAS studies.Semantic proximity Read ↗

A complex polymorphic region in the brain-derived neurotrophic factor (BDNF) gene confers susceptibility to bipolar disorder and affects transcriptional activity.Semantic proximity Read ↗

The brain-derived neurotrophic factor gene confers susceptibility to bipolar disorder: evidence from a family-based association study.Semantic proximity Read ↗

The BDNF gene Val66Met polymorphism as a modifier of psychiatric disorder susceptibility: progress and controversy.Semantic proximity Read ↗

Evidence for a relationship between genetic variants at the brain-derived neurotrophic factor (BDNF) locus and major depression.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.