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Article

Genetic variation in the brain derived neurotrophic factor gene in Alzheimer's disease.

American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics - 5 Apr 2005

Bodner Sara M, Berrettini Wade, van Deerlin Vivianna, Bennett David A, Wilson Robert S, Trojanowski John Q, Arnold Steven E

Abstract excerpt

Genes known to contribute to the genetic predisposition to Alzheimer's disease (AD) are active in pathways of neurodegeneration but explain only a minority of the genetic contribution to AD. A protein of importance in cerebral neurodegeneration is the brain-derived neurotrophic factor (BDNF). Variations in two single-nucleotide polymorphisms (SNPs) within the BDNF gene have previously been associated with AD, and...

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Identifiers

PMID: 15635706
DOI: 10.1002/ajmg.b.30154

Genes

BDNF
APOE

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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