Article
Lack of evidence for a genetic association between FGF20 and Parkinson's disease in Finnish and Greek patients.
BMC neurology - 20 Jun 2005
Clarimon Jordi, Xiromerisiou Georgia, Eerola Johanna, Gourbali Vanesa, Hellström Olli, Dardiotis Euthimios, Peuralinna Terhi, Papadimitriou Alexandros, Hadjigeorgiou George M, Tienari Pentti J, Singleton Andrew B
Abstract excerpt
BACKGROUND: Fibroblast growth factor 20 (FGF20) is a neurotrophic factor preferentially expressed in the substantia nigra of rat brain and could be involved in dopaminergic neurons survival. Recently, a strong genetic association has been found between FGF20 gene and the risk of suffering from Parkinson's disease (PD). Our aim was to replicate this association in two independent populations. METHODS: Allelic,...
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