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Article

Brain-derived neurotrophic factor G196A polymorphism and clinical features in Parkinson's disease.

Acta neurologica Scandinavica - 1 Jul 2010

Gao L, Díaz-Corrales F J, Carrillo F, Díaz-Martín J, Caceres-Redondo M T, Carballo M, Palomino A, López-Barneo J, Mir P

Abstract excerpt

OBJECTIVES: Parkinson's disease (PD) is characterized by the dopaminergic neuronal death in substantia nigra, and genetic factors appear to be involved in the pathophysiology of this disease. Brain-derived neurotrophic factor (BDNF) is widely expressed in the central nervous system and is necessary for the survival of dopaminergic neurons in substantia nigra. G196A, a common polymorphism of the BDNF gene, not...

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Source

Identifiers

PMID: 20085561
DOI: 10.1111/j.1600-0404.2009.01253.x

Genes

BDNF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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Brain-derived neurotrophic factor G196A polymorphism and clinical features in Parkinson's disease.PMID 20085561Read ↗

Association between the BDNF G196A and C270T polymorphisms and Parkinson's disease: a meta-analysis.Semantic proximity Read ↗

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BDNF Val66Met polymorphism is associated with cognitive impairment in Italian patients with Parkinson's disease.Semantic proximity Read ↗

BDNF G196A (Val66Met) polymorphism associated with cognitive impairment in Parkinson's disease.Semantic proximity Read ↗

BDNF 196 G/A and 270 C/T polymorphisms and susceptibility to Parkinson's disease: a meta-analysis.Semantic proximity Read ↗

The 712A/G polymorphism of Brain-derived neurotrophic factor is associated with Parkinson's disease but not Major Depressive Disorder in a Chinese Han population.Semantic proximity Read ↗

Association of brain-derived neurotrophic factor (BDNF) Val66Met polymorphism with Parkinson's disease in a Greek population.Semantic proximity Read ↗

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