Article
Cyclooxygenase-2 polymorphisms and susceptibility to esophageal cancer: a meta-analysis.
The Tohoku journal of experimental medicine - 1 Feb 2011
Liang Yuan, Liu Jia-Li, Wu Yan, Zhang Zhen-Yong, Wu Rong
Abstract excerpt
Esophageal cancer (EC) is one of the most common cancers worldwide with 5-year survival rate less than 10%. However, there is a lack of specific genetic markers that could help better understanding the mechanisms of esophageal carcinogenesis, improving the detection rate of EC, and distinguishing histological types. Cyclooxygenase-2 (COX-2) as an inducible enzyme in cancer development and progression is involved...
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